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Symbol
Name
ID
Mir21a
microRNA 21a
MGI:2676885
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal thymus morphology
abnormal thymus corticomedullary boundary morphology
enlarged thymus
enlarged spleen
decreased leukocyte cell number
abnormal spleen morphology
intermingled spleen red and white pulp
abnormal cytokine level
abnormal interferon level
abnormal interleukin level
enlarged lymph nodes
increased susceptibility to type I hypersensitivity reaction
increased susceptibility to type IV hypersensitivity reaction
abnormal cytokine secretion
increased interferon-gamma secretion
increased interleukin-12 secretion
decreased interleukin-4 secretion
Availability Mouse Genotype
Mir21atm1.1Mer/Mir21atm1.1Mer
Gt(ROSA)26Sortm1(tTA,tetO-Mir21)Fjsl/Gt(ROSA)26Sor+
Tg(Nes-cre)1Wmz/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory